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Differential Regulation of Synaptic Vesicle Tethering and Docking by UNC-18 and TOM-1

The assembly of SNARE complexes between syntaxin, SNAP-25 and synaptobrevin is required to prime synaptic vesicles for fusion. Since Munc18 and tomosyn compete for syntaxin interactions, the interplay between these proteins is predicted to be important in regulating synaptic transmission. We explore...

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Autori principali: Gracheva, Elena O., Maryon, Ed B., Berthelot-Grosjean, Martine, Richmond, Janet E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Research Foundation 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3059690/
https://ncbi.nlm.nih.gov/pubmed/21423527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnsyn.2010.00141
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