Membrane-Bound Catechol-O-Methyl Transferase in Cortical Neurons and Glial Cells is Intracellularly Oriented

Catechol-O-methyl transferase (COMT) is involved in the inactivation of dopamine in brain regions in which the dopamine transporter (DAT1) is sparsely expressed. The membrane-bound isoform of COMT (MB-COMT) is the predominantly expressed form in the mammalian central nervous system (CNS). It has bee...

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Autori principali: Schott, Björn H., Frischknecht, Renato, Debska-Vielhaber, Grazyna, John, Nora, Behnisch, Gusalija, Düzel, Emrah, Gundelfinger, Eckart D., Seidenbecher, Constanze I.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Research Foundation 2010
Soggetti:
Psychiatry
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3059651/
https://ncbi.nlm.nih.gov/pubmed/21423451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fpsyt.2010.00142
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