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Genetic variation of the RASGRF1 regulatory region affects human hippocampus-dependent memory

The guanine nucleotide exchange factor RASGRF1 is an important regulator of intracellular signaling and neural plasticity in the brain. RASGRF1-deficient mice exhibit a complex phenotype with learning deficits and ocular abnormalities. Also in humans, a genome-wide association study has identified t...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Barman, Adriana, Assmann, Anne, Richter, Sylvia, Soch, Joram, Schütze, Hartmut, Wüstenberg, Torsten, Deibele, Anna, Klein, Marieke, Richter, Anni, Behnisch, Gusalija, Düzel, Emrah, Zenker, Martin, Seidenbecher, Constanze I., Schott, Björn H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4010733/
https://ncbi.nlm.nih.gov/pubmed/24808846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnhum.2014.00260
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