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DNA methylation in hereditary persistence of fetal hemoglobin (HPFH-2).

Recent studies show that the region of DNA brought into close proximity to the fetal gamma-globin genes in deletional forms of hereditary persistence of fetal hemoglobin (HPFH) is selectively hypomethylated (and presumably active) in normal erythroid tissue. This region is normally located approxima...

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Dettagli Bibliografici
Autori principali: Poncz, M, Sutton, M, Delgrosso, K, Schwartz, E, Surrey, S
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1987
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC305954/
https://ncbi.nlm.nih.gov/pubmed/3601670
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