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NEPHROBLASTOMA OVEREXPRESSED (NOV) INDUCES GREMLIN IN ST-2 STROMAL CELL LINES BY POST-TRANSCRIPTIONAL MECHANISMS

Nephroblastoma overexpressed (Nov) inhibits osteoblastogenesis in part because it binds bone morphogenetic protein (BMP)-2. In the present study, we investigated whether Nov regulated the expression of the BMP antagonist gremlin. Overexpression of Nov increased gremlin mRNA levels in ST-2 cells, and...

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Hlavní autoři: Smerdel-Ramoya, Anna, Zanotti, Stefano, Canalis, Ernesto
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3059361/
https://ncbi.nlm.nih.gov/pubmed/21268093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.22985
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