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Catalytic Mechanism and Three-Dimensional Structure of Adenine Deaminase
Adenine deaminase (ADE) catalyzes the conversion of adenine to hypoxanthine and ammonia. The enzyme isolated from Escherichia coli using standard expression conditions was low for the deamination of adenine (k(cat) = 2.0 s(−1); k(cat)/K(m) = 2.5 × 10(3) M(−1) s(−1)). However, when iron was sequester...
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| Main Authors: | , , , , , , , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2011
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3059353/ https://ncbi.nlm.nih.gov/pubmed/21247091 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi101788n |
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