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ERK1/2 deactivation enhances cytoplasmic Nur77 expression level and improves the apoptotic effect of fenretinide in human liver cancer cells

Fenretinide, a synthetic retinoid, is a promising anticancer agent based on many in vitro, animal, and chemoprevention clinical trial studies. However, cells such as HepG2 human liver cancer cells are resistant to the apoptotic effect of fenretinide. Previously, we have shown that fenretinide-induce...

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Autori principali: Yang, Hui, Nie, Yuqiang, Li, Yuyuan, Wan, Yu-Jui Yvonne
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3059345/
https://ncbi.nlm.nih.gov/pubmed/21241664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2011.01.005
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