Ha-Ras stabilization mediates pro-fibrotic signals in dermal fibroblasts

BACKGROUND: Scleroderma (systemic sclerosis; SSc) is a clinically heterogeneous and often lethal acquired disorder of the connective tissue that is characterized by vascular, immune/inflammatory and fibrotic manifestations. Tissue fibrosis is the main cause of morbidity and mortality in SSc and an u...

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Autores principales: Smaldone, Silvia, Olivieri, Jacopo, Gusella, Gabriele Luca, Moroncini, Gianluca, Gabrielli, Armando, Ramirez, Francesco
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2011
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3059295/
https://ncbi.nlm.nih.gov/pubmed/21362163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1755-1536-4-8
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