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Conformational changes in Dnm1 support a contractile mechanism for mitochondrial fission

Mitochondria are dynamic organelles that undergo cycles of fission and fusion. The yeast dynamin-related protein, Dnm1, has been localized to sites of mitochondrial division. Using cryo-electron microscopy (cryo-EM), we have determined the three-dimensional structure of Dnm1 in a GTP-bound state. Th...

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Bibliographische Detailangaben
Hauptverfasser: Mears, Jason A., Lackner, Laura L., Fang, Shunming, Ingerman, Elena, Nunnari, Jodi, Hinshaw, Jenny E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3059246/
https://ncbi.nlm.nih.gov/pubmed/21170049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.1949
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