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Conformational changes in Dnm1 support a contractile mechanism for mitochondrial fission
Mitochondria are dynamic organelles that undergo cycles of fission and fusion. The yeast dynamin-related protein, Dnm1, has been localized to sites of mitochondrial division. Using cryo-electron microscopy (cryo-EM), we have determined the three-dimensional structure of Dnm1 in a GTP-bound state. Th...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2010
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3059246/ https://ncbi.nlm.nih.gov/pubmed/21170049 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.1949 |
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