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Preparation of base-modified nucleosides suitable for non-radioactive label attachment and their incorporation into synthetic oligodeoxyribonucleotides.

A very mild and efficient procedure has been developed for the preparation of C-5 substituted deoxyuridines. The substituent carries a masked primary aliphatic amino group. These compounds are readily converted into their phosphoramidites and can be used to prepare oligonucleotides carrying one or m...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Principais autores: Haralambidis, J, Chai, M, Tregear, G W
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 1987
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC305923/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3110740/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/15.12.4857
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