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Treatment with LXR agonists after focal cerebral ischemia prevents brain damage

Stroke is characterized by massive inflammation in areas surrounding the injury that magnifies damage to the brain. The Liver X Receptors (LXRs) are nuclear receptors that regulate cholesterol, lipid, and glucose metabolism. Synthetic LXR agonists have potent anti-inflammatory properties in a variet...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Sironi, Luigi, Mitro, Nico, Cimino, Mauro, Gelosa, Paolo, Guerrini, Uliano, Tremoli, Elena, Saez, Enrique
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3059157/
https://ncbi.nlm.nih.gov/pubmed/18789330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2008.08.035
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