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Proprotein Convertases Process Pmel17 during Secretion

Pmel17 is a melanocyte/melanoma-specific protein that traffics to melanosomes where it forms a fibrillar matrix on which melanin gets deposited. Before being cleaved into smaller fibrillogenic fragments the protein undergoes processing by proprotein convertases, a class of serine proteases that typi...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Leonhardt, Ralf M., Vigneron, Nathalie, Rahner, Christoph, Cresswell, Peter
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3059051/
https://ncbi.nlm.nih.gov/pubmed/21247888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.168088
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