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BAG3 Expression in Glioblastoma Cells Promotes Accumulation of Ubiquitinated Clients in an Hsp70-dependent Manner

Disposal of damaged proteins and protein aggregates is a prerequisite for the maintenance of cellular homeostasis and impairment of this disposal can lead to a broad range of pathological conditions, most notably in brain-associated disorders including Parkinson and Alzheimer diseases, and cancer. I...

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Autors principals: Gentilella, Antonio, Khalili, Kamel
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3059025/
https://ncbi.nlm.nih.gov/pubmed/21233200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.175836
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