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Expression of Water-soluble, Ligand-binding Concatameric Extracellular Domains of the Human Neuronal Nicotinic Receptor α4 and β2 Subunits in the Yeast Pichia pastoris: GLYCOSYLATION IS NOT REQUIRED FOR LIGAND BINDING

Nicotinic acetylcholine receptors (nAChRs) are ligand-gated cation channels that are responsible for cell communication via the neurotransmitter acetylcholine. The predominant nAChR subtype in the mammalian brain with a high affinity for nicotine is composed of α4 and β2 subunits. This nAChR subtype...

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Bibliografski detalji
Glavni autori: Stergiou, Christos, Zisimopoulou, Paraskevi, Tzartos, Socrates J.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2011
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3059009/
https://ncbi.nlm.nih.gov/pubmed/21252231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.171645
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