Regulator of Calcineurin 1 (RCAN1) Facilitates Neuronal Apoptosis through Caspase-3 Activation

Individuals with Down syndrome (DS) will inevitably develop Alzheimer disease (AD) neuropathology sometime after middle age, which may be attributable to genes triplicated in individuals with DS. The characteristics of AD neuropathology include neuritic plaques, neurofibrillary tangles, and neuronal...

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Detalhes bibliográficos
Main Authors: Sun(孙, Xiulian, 秀莲), Wu(吴, Yili, 伊丽), Chen, Bin, Zhang, Zhuohua, Zhou, Weihui, Tong(童, Yigang, 贻刚), Yuan, Junying, Xia, Kun, Gronemeyer, Hinrich, Flavell, Richard A., Song(宋, Weihong, 伟宏)
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Molecular Bases of Disease
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3059004/
https://ncbi.nlm.nih.gov/pubmed/21216952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.177519
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