Nanomechanics of the Cadherin Ectodomain: “CANALIZATION” BY Ca(2+) BINDING RESULTS IN A NEW MECHANICAL ELEMENT

Cadherins form a large family of calcium-dependent cell-cell adhesion receptors involved in development, morphogenesis, synaptogenesis, differentiation, and carcinogenesis through signal mechanotransduction using an adaptor complex that connects them to the cytoskeleton. However, the molecular mecha...

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Bibliografiske detaljer
Main Authors: Oroz, Javier, Valbuena, Alejandro, Vera, Andrés Manuel, Mendieta, Jesús, Gómez-Puertas, Paulino, Carrión-Vázquez, Mariano
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2011
Fag:
Molecular Biophysics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3058956/
https://ncbi.nlm.nih.gov/pubmed/21177864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.170399
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