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Nanomechanics of the Cadherin Ectodomain: “CANALIZATION” BY Ca(2+) BINDING RESULTS IN A NEW MECHANICAL ELEMENT
Cadherins form a large family of calcium-dependent cell-cell adhesion receptors involved in development, morphogenesis, synaptogenesis, differentiation, and carcinogenesis through signal mechanotransduction using an adaptor complex that connects them to the cytoskeleton. However, the molecular mecha...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Biochemistry and Molecular Biology
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3058956/ https://ncbi.nlm.nih.gov/pubmed/21177864 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.170399 |
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