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Structure of a bacterial ribonuclease P holoenzyme in complex with tRNA

Ribonuclease (RNase) P is the universal ribozyme responsible for 5′-end tRNA processing. We report the crystal structure of the Thermotoga maritima RNase P holoenzyme in complex with tRNA(Phe). The 154 kDa complex consists of a large catalytic RNA (P RNA), a small protein cofactor, and mature tRNA....

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Détails bibliographiques
Auteurs principaux: Reiter, Nicholas J., Osterman, Amy, Torres-Larios, Alfredo, Swinger, Kerren K., Pan, Tao, Mondragón, Alfonso
Format: Artigo
Langue:Inglês
Publié: 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3058908/
https://ncbi.nlm.nih.gov/pubmed/21076397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature09516
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