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Src activates Abl to augment Robo1 expression in order to promote tumor cell migration

Cell migration is an essential step in cancer invasion and metastasis. A number of orchestrated cellular events involving tyrosine kinases and signaling receptors enable cancer cells to dislodge from primary tumors and colonize elsewhere in the body. For example, activation of the Src and Abl kinase...

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Detalhes bibliográficos
Main Authors: Khusial, P. Raaj, Vadla, Bhaskar, Krishnan, Harini, Ramlall, Trudy F., Shen, Yongquan, Ichikawa, Hitoshi, Geng, Jian-Guo, Goldberg, Gary S.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3058788/
https://ncbi.nlm.nih.gov/pubmed/21301049
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