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Hypertension Induced by VEGF Signaling Pathway Inhibition: Mechanisms and Potential Use as a Biomarker

Drugs that inhibit the vascular endothelial growth factor (VEGF) signaling pathway are a rapidly growing chemotherapy class for treatment of solid tumors. This “targeted therapy” is more specific than traditional chemotherapy, causing fewer side effects. However, VEGF-targeted therapies cause hypert...

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Détails bibliographiques
Auteurs principaux: Robinson, Emily S., Khankin, Eliyahu V., Karumanchi, S. Ananth, Humphreys, Benjamin D.
Format: Artigo
Langue:Inglês
Publié: 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3058726/
https://ncbi.nlm.nih.gov/pubmed/21146124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.semnephrol.2010.09.007
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