ChIP-on-chip analysis reveals angiopoietin 2 (Ang2, ANGPT2) as a novel target of steroidogenic factor-1 (SF-1, NR5A1) in the human adrenal gland

The nuclear receptor steroidogenic factor-1 (SF-1, NR5A1) is a key regulator of adrenal and gonadal biology. Disruption of SF-1 can lead to disorders of adrenal development, while increased SF-1 dosage has been associated with adrenocortical tumorigenesis. We aimed to identify a novel subset of SF-1...

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Bibliografiske detaljer
Main Authors: Ferraz-de-Souza, Bruno, Lin, Lin, Shah, Sonia, Jina, Nipurna, Hubank, Mike, Dattani, Mehul T., Achermann, John C.
Format: Artigo
Sprog:Inglês
Udgivet: Federation of American Societies for Experimental Biology 2011
Fag:
Research Communications
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3058709/
https://ncbi.nlm.nih.gov/pubmed/21163858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.10-170522
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