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Contribution of IL-17–producing γδ T cells to the efficacy of anticancer chemotherapy

By triggering immunogenic cell death, some anticancer compounds, including anthracyclines and oxaliplatin, elicit tumor-specific, interferon-γ–producing CD8(+) αβ T lymphocytes (Tc1 CTLs) that are pivotal for an optimal therapeutic outcome. Here, we demonstrate that chemotherapy induces a rapid and...

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Detalhes bibliográficos
Main Authors: Ma, Yuting, Aymeric, Laetitia, Locher, Clara, Mattarollo, Stephen R., Delahaye, Nicolas F., Pereira, Pablo, Boucontet, Laurent, Apetoh, Lionel, Ghiringhelli, François, Casares, Noëlia, Lasarte, Juan José, Matsuzaki, Goro, Ikuta, Koichi, Ryffel, Bernard, Benlagha, Kamel, Tesnière, Antoine, Ibrahim, Nicolas, Déchanet-Merville, Julie, Chaput, Nathalie, Smyth, Mark J., Kroemer, Guido, Zitvogel, Laurence
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3058575/
https://ncbi.nlm.nih.gov/pubmed/21383056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20100269
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