Differentiation between glioma and radiation necrosis using molecular magnetic resonance imaging of endogenous proteins and peptides

Distinguishing tumor recurrence from radiation necrosis following brain tumor therapy remains a major clinical challenge. Here we demonstrate the ability to distinguish these lesions using the amide proton transfer (APT) MRI signals of endogenous cellular proteins and peptides as an imaging biomarke...

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Autori principali: Zhou, Jinyuan, Tryggestad, Erik, Wen, Zhibo, Lal, Bachchu, Zhou, Tingting, Grossman, Rachel, Wang, Silun, Yan, Kun, Fu, De-Xue, Ford, Eric, Tyler, Betty, Blakeley, Jaishri, Laterra, John, van Zijl, Peter C.M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3058561/
https://ncbi.nlm.nih.gov/pubmed/21170048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.2268
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