HCN Channelopathy in External Globus Pallidus Neurons in Models of Parkinson’s Disease

Parkinson’s disease (PD) is a common neurodegenerative disorder characterized by a profound motor disability that is traceable to the emergence of synchronous, rhythmic spiking in neurons of the external segment of the globus pallidus (GPe). The origins of this pathophysiology are poorly defined. Fo...

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Autores principales: Chan, C. Savio, Glajch, Kelly E., Gertler, Tracy S., Guzman, Jaime N., Mercer, Jeff N., Lewis, Alan S., Goldberg, Alan B., Tkatch, Tatiana, Shigemoto, Ryuichi, Fleming, Sheila M., Chetkovich, Dane M., Osten, Pavel, Kita, Hitoshi, Surmeier, D. James
Formato: Artigo
Lenguaje:Inglês
Publicado: 2010
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3058391/
https://ncbi.nlm.nih.gov/pubmed/21076425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.2692
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