HCN Channelopathy in External Globus Pallidus Neurons in Models of Parkinson’s Disease

Parkinson’s disease (PD) is a common neurodegenerative disorder characterized by a profound motor disability that is traceable to the emergence of synchronous, rhythmic spiking in neurons of the external segment of the globus pallidus (GPe). The origins of this pathophysiology are poorly defined. Fo...

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Detalhes bibliográficos
Main Authors: Chan, C. Savio, Glajch, Kelly E., Gertler, Tracy S., Guzman, Jaime N., Mercer, Jeff N., Lewis, Alan S., Goldberg, Alan B., Tkatch, Tatiana, Shigemoto, Ryuichi, Fleming, Sheila M., Chetkovich, Dane M., Osten, Pavel, Kita, Hitoshi, Surmeier, D. James
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3058391/
https://ncbi.nlm.nih.gov/pubmed/21076425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.2692
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