Prognostic and Predictive Value of the 21-Gene Recurrence Score Assay in a Randomized Trial of Chemotherapy for Postmenopausal, Node-Positive, Estrogen Receptor-Positive Breast Cancer

BACKGROUND: The 21-gene Recurrence Score assay (RS) is prognostic for women with node-negative, estrogen receptor (ER)-positive breast cancer (BC) treated with tamoxifen. A low RS predicts little benefit of chemotherapy. For node-positive BC, we investigated whether RS was prognostic in women treate...

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Main Authors: Albain, Kathy S., Barlow, William E., Shak, Steven, Hortobagyi, Gabriel N., Livingston, Robert B., Yeh, I-Tien, Ravdin, Peter, Bugarini, Roberto, Baehner, Frederick L., Davidson, Nancy E., Sledge, George W., Winer, Eric P., Hudis, Clifford, Ingle, James N., Perez, Edith A., Pritchard, Kathleen I., Shepherd, Lois, Gralow, Julie R., Yoshizawa, Carl, Allred, D. Craig, Osborne, C. Kent, Hayes, Daniel F.
Format: Artigo
Language:Inglês
Published: 2009
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3058239/
https://ncbi.nlm.nih.gov/pubmed/20005174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S1470-2045(09)70314-6
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