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Lactation defect in mice lacking the helix–loop–helix inhibitor Id2

Id proteins are thought to be negative regulators of cell differentiation and positive regulators of cell proliferation. Mammary glands of Id2(–/–) female mice reveal severely impaired lobulo-alveolar development during pregnancy. Id2(–/–) mammary epithelia show no precocious maturation, but instead...

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Detalhes bibliográficos
Publicado no:EMBO J
Main Authors: Mori, Seiichi, Nishikawa, Shin-Ichi, Yokota, Yoshifumi
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC305805/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11060028/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/19.21.5772
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