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Lactation defect in mice lacking the helix–loop–helix inhibitor Id2

Id proteins are thought to be negative regulators of cell differentiation and positive regulators of cell proliferation. Mammary glands of Id2(–/–) female mice reveal severely impaired lobulo-alveolar development during pregnancy. Id2(–/–) mammary epithelia show no precocious maturation, but instead...

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Autors principals: Mori, Seiichi, Nishikawa, Shin-Ichi, Yokota, Yoshifumi
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2000
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC305805/
https://ncbi.nlm.nih.gov/pubmed/11060028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.21.5772
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