CYP2D6 Inhibition and Breast Cancer Recurrence in a Population-Based Study in Denmark

BACKGROUND: Cytochrome P450 2D6 (CYP2D6) inhibition reduces the concentration of 4-hydroxylated tamoxifen metabolites, but the clinical relevance remains uncertain. METHODS: We conducted a large case–control study nested in the population of 11 251 women aged 35–69 years at diagnosis of stage I–III...

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Detalhes bibliográficos
Main Authors: Lash, Timothy L., Cronin-Fenton, Deirdre, Ahern, Thomas P., Rosenberg, Carol L., Lunetta, Kathryn L., Silliman, Rebecca A., Garne, Jens Peter, Sørensen, Henrik Toft, Hellberg, Ylva, Christensen, Mariann, Pedersen, Lars, Hamilton-Dutoit, Stephen
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2011
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3057982/
https://ncbi.nlm.nih.gov/pubmed/21325141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnci/djr010
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