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GABAergic dysfunction mediates autism-like stereotypies and Rett syndrome phenotypes
Mutations in the X-linked MECP2, which encodes the transcriptional regulator methyl-CpG-binding protein 2 (MeCP2) cause Rett syndrome (RTT) and several neurodevelopmental disorders including cognitive disorders, autism, juvenile-onset schizophrenia, and encephalopathy with early lethality. RTT is ch...
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Main Authors: | , , , , , , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2010
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3057962/ https://ncbi.nlm.nih.gov/pubmed/21068835 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature09582 |
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