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GABAergic dysfunction mediates autism-like stereotypies and Rett syndrome phenotypes

Mutations in the X-linked MECP2, which encodes the transcriptional regulator methyl-CpG-binding protein 2 (MeCP2) cause Rett syndrome (RTT) and several neurodevelopmental disorders including cognitive disorders, autism, juvenile-onset schizophrenia, and encephalopathy with early lethality. RTT is ch...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Chao, Hsiao-Tuan, Chen, Hongmei, Samaco, Rodney C., Xue, Mingshan, Chahrour, Maria, Yoo, Jong, Neul, Jeffrey L., Gong, Shiaoching, Lu, Hui-Chen, Heintz, Nathaniel, Ekker, Marc, Rubenstein, John L.R., Noebels, Jeffrey L., Rosenmund, Christian, Zoghbi, Huda Y.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: 2010
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3057962/
https://ncbi.nlm.nih.gov/pubmed/21068835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature09582
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