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LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing

Little is known about the protein constituents of autophagosome membranes in mammalian cells. Here we demonstrate that the rat microtubule-associated protein 1 light chain 3 (LC3), a homologue of Apg8p essential for autophagy in yeast, is associated to the autophagosome membranes after processing. T...

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Detalhes bibliográficos
Main Authors: Kabeya, Yukiko, Mizushima, Noboru, Ueno, Takashi, Yamamoto, Akitsugu, Kirisako, Takayoshi, Noda, Takeshi, Kominami, Eiki, Ohsumi, Yoshinori, Yoshimori, Tamotsu
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2000
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC305793/
https://ncbi.nlm.nih.gov/pubmed/11060023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.21.5720
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