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LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing

Little is known about the protein constituents of autophagosome membranes in mammalian cells. Here we demonstrate that the rat microtubule-associated protein 1 light chain 3 (LC3), a homologue of Apg8p essential for autophagy in yeast, is associated to the autophagosome membranes after processing. T...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:EMBO J
Prif Awduron: Kabeya, Yukiko, Mizushima, Noboru, Ueno, Takashi, Yamamoto, Akitsugu, Kirisako, Takayoshi, Noda, Takeshi, Kominami, Eiki, Ohsumi, Yoshinori, Yoshimori, Tamotsu
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group 2000
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC305793/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11060023/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/19.21.5720
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