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Carbamazepine co-administration with an oral contraceptive: effects on steroid pharmacokinetics, ovulation, and bleeding
PURPOSE: Anti-epileptic drugs (AEDs) are widely used in reproductive-age women. The AED carbamazepine (CBZ) induces the hepatic cytochrome p450 system accelerating hormone metabolism. We sought to assess the pharmacodynamic effects of CBZ on breakthrough bleeding and ovulation during OC use. METHODS...
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| Main Authors: | , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2011
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3057928/ https://ncbi.nlm.nih.gov/pubmed/21204827 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1528-1167.2010.02917.x |
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