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Heparanase Plays a Dual Role in Driving Hepatocyte Growth Factor (HGF) Signaling by Enhancing HGF Expression and Activity

Hepatocyte growth factor (HGF) is a heparin-binding cytokine that enhances growth, motility, and angiogenesis of many tumor types, including multiple myeloma where it is often highly expressed. However, little is known regarding what controls HGF level and activity in these tumors. Evaluation of bon...

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Bibliografiske detaljer
Main Authors: Ramani, Vishnu C., Yang, Yang, Ren, Yongsheng, Nan, Li, Sanderson, Ralph D.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3057851/
https://ncbi.nlm.nih.gov/pubmed/21131364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.183277
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