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Osmotic stress response in Dictyostelium is mediated by cAMP

DokA, a homolog of bacterial hybrid histidine kinases, is essential for hyperosmotic stress resistance in Dictyostelium. We show that a transient intracellular cAMP signal, dependent on the presence of DokA, is generated in response to an osmotic shock. This variation of cAMP levels contributes to s...

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Détails bibliographiques
Publié dans:EMBO J
Auteurs principaux: Ott, Alexander, Oehme, Felix, Keller, Heike, Schuster, Stephan C.
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2000
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC305785/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11060029/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/19.21.5782
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