Activation Loop Phosphorylation of ERK3/ERK4 by Group I p21-activated Kinases (PAKs) Defines a Novel PAK-ERK3/4-MAPK-activated Protein Kinase 5 Signaling Pathway

Classical mitogen-activated protein (MAP) kinases are activated by dual phosphorylation of the Thr-Xxx-Tyr motif in their activation loop, which is catalyzed by members of the MAP kinase kinase family. The atypical MAP kinases extracellular signal-regulated kinase 3 (ERK3) and ERK4 contain a single...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Déléris, Paul, Trost, Matthias, Topisirovic, Ivan, Tanguay, Pierre-Luc, Borden, Katherine L. B., Thibault, Pierre, Meloche, Sylvain
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2011
Sujets:
Signal Transduction
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3057823/
https://ncbi.nlm.nih.gov/pubmed/21177870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.181529
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