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Influencing Hematopoietic Differentiation of Mouse Embryonic Stem Cells using Soluble Heparin and Heparan Sulfate Saccharides

Heparan sulfate proteoglycans (HSPG) encompass some of the most abundant macromolecules on the surface of almost every cell type. Heparan sulfate (HS) chains provide a key interaction surface for the binding of numerous proteins such as growth factors and morphogens, helping to define the ability of...

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Autors principals: Holley, Rebecca J., Pickford, Claire E., Rushton, Graham, Lacaud, Georges, Gallagher, John T., Kouskoff, Valerie, Merry, Catherine L. R.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3057799/
https://ncbi.nlm.nih.gov/pubmed/21148566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.178483
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