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The Solution Structure of Heparan Sulfate Differs from That of Heparin: IMPLICATIONS FOR FUNCTION

The highly sulfated polysaccharides heparin and heparan sulfate (HS) play key roles in the regulation of physiological and pathophysiological processes. Despite its importance, no molecular structures of free HS have been reported up to now. By combining analytical ultracentrifugation, small angle x...

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Detalhes bibliográficos
Main Authors: Khan, Sanaullah, Rodriguez, Elizabeth, Patel, Rima, Gor, Jayesh, Mulloy, Barbara, Perkins, Stephen J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3137059/
https://ncbi.nlm.nih.gov/pubmed/21576246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.226027
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