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Telomerase reactivation reverses tissue degeneration in aged telomerase deficient mice

An ageing world population has fueled interest in regenerative remedies that may stem declining organ function and maintain fitness. Unanswered is whether elimination of intrinsic instigators driving age-associated degeneration can reverse, as opposed to simply arrest, various afflictions of the age...

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Bibliografiska uppgifter
Huvudupphovsmän: Jaskelioff, Mariela, Muller, Florian L., Paik, Ji-Hye, Thomas, Emily, Jiang, Shan, Adams, Andrew, Sahin, Ergun, Kost-Alimova, Maria, Protopopov, Alexei, Cadiñanos, Juan, Horner, James W., Maratos-Flier, Eleftheria, DePinho, Ronald A.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2010
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3057569/
https://ncbi.nlm.nih.gov/pubmed/21113150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature09603
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