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Tocilizumab in Systemic Lupus Erythematosus – Safety, Preliminary Efficacy, and Impact on Circulating Plasma Cells
OBJECTIVE: To assess the safety of interleukin-6 receptor inhibition and to collect preliminary data on clinical and immunologic efficacy of tocilizumab in patients with systemic lupus erythematosus (SLE). METHODS: In an open label, dose-escalating, Phase I study, 16 patients with mild to moderate d...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3057537/ https://ncbi.nlm.nih.gov/pubmed/20112381 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.27221 |
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