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Rationale for interleukin-6 blockade in systemic lupus erythematosus

Interleukin-6 (IL-6) is a pleiotropic cytokine with a wide range of biological activities that plays an important role in immune regulation and inflammation. Among other actions, it induces terminal differentiation of B lymphocytes into antibody-forming cells and the differentiation of T cells into...

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Detalhes bibliográficos
Main Authors: Tackey, E, Lipsky, PE, Illei, GG
Formato: Artigo
Idioma:Inglês
Publicado em: 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2014821/
https://ncbi.nlm.nih.gov/pubmed/15230289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1191/0961203304lu1023oa
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