Effects of posttraumatic carbamylated erythropoietin therapy on reducing lesion volume and hippocampal cell loss, enhancing angiogenesis and neurogenesis, and improving functional outcome in rats following traumatic brain injury

OBJECT: Carbamylated erythropoietin (CEPO) is a modified erythropoietin molecule that does not affect hematocrit. In this study, we compared the efficacy of a single dose with triple dose of CEPO treatment of traumatic brain injury (TBI) in rats. METHODS: TBI was induced by controlled cortical impac...

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Detalhes bibliográficos
Main Authors: Xiong, Ye, Mahmood, Asim, Zhang, Yanlu, Meng, Yuling, Zhang, Zheng Gang, Qu, Changsheng, Sager, Thomas N., Chopp, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3057520/
https://ncbi.nlm.nih.gov/pubmed/21073254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3171/2010.10.JNS10925
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