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Delayed administration of erythropoietin reduces hippocampal cell loss, enhances angiogenesis and neurogenesis, and improves functional outcome following traumatic brain injury in rats: comparison of treatment with single dose and triple dose

OBJECT: This study was designed to investigate delayed erythropoietin (EPO) treatment for traumatic brain injury (TBI) in rats comparing efficacy of a single dose with triple doses. METHODS: Young adult male Wistar rats were randomly divided into the following groups: 1) Sham group (n = 6); 2) TBI +...

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Autori principali: Xiong, Ye, Mahmood, Asim, Meng, Yuling, Zhang, Yanlu, Qu, Changsheng, Schallert, Timothy, Chopp, Michael
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2898921/
https://ncbi.nlm.nih.gov/pubmed/19817538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3171/2009.9.JNS09844
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