Cap binding and immune evasion revealed by Lassa nucleoprotein structure

Lassa fever virus (LASV) causes thousands of deaths yearly and is a biological threat agent, for which there is no vaccine and limited therapy1. The nucleoprotein (NP) of LASV plays essential roles in viral RNA synthesis and immune suppression2-6, the molecular mechanisms of which are poorly underst...

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Detalhes bibliográficos
Main Authors: Qi, Xiaoxuan, Lan, Shuiyun, Wang, Wenjian, Schelde, Lisa McLay, Dong, Haohao, Wallat, Gregor D., Ly, Hinh, Liang, Yuying, Dong, Changjiang
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3057469/
https://ncbi.nlm.nih.gov/pubmed/21085117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature09605
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