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Associations of tryptophan hydroxylase gene polymorphisms with IBS
BACKGROUND: Alterations in serotonin (5-HT) are suspected in the pathophysiology of irritable bowel syndrome (IBS). Tryptophan hydroxylase (TPH) is the rate-limiting enzyme in the biosynthesis of serotonin and has two isoforms, TPH1 and TPH2. Genetic variants in both genes have been studied in vario...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2010
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3057463/ https://ncbi.nlm.nih.gov/pubmed/21073637 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2982.2010.01623.x |
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