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TPH Gene Polymorphisms Are Associated With Disease Perception and Quality of Life in Women With Irritable Bowel Syndrome

The aims of this exploratory study were to examine whether tryptophan hydroxylase (TPH) gene polymorphisms are associated with psychosocial factors in women with irritable bowel syndrome (IBS). TPH is the rate-limiting enzyme in the biosynthesis of serotonin and has two isoforms, TPH1 and TPH2. Four...

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Autors principals: Jun, Sang-Eun, Kohen, Ruth, Cain, Kevin C., Jarrett, Monica E., Heitkemper, Margaret M.
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3766405/
https://ncbi.nlm.nih.gov/pubmed/23172723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1099800412466694
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