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Dihydropteridine Reductase as an Alternative to Dihydrofolate Reductase for Synthesis of Tetrahydrofolate in Thermus thermophilus

A strategy devised to isolate a gene coding for a dihydrofolate reductase from Thermus thermophilus DNA delivered only clones harboring instead a gene (the T. thermophilus dehydrogenase [DH(Tt)] gene) coding for a dihydropteridine reductase which displays considerable dihydrofolate reductase activit...

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Bibliografische Detailangaben
Veröffentlicht in:J Bacteriol
Hauptverfasser: Wilquet, Valérie, Van de Casteele, Mark, Gigot, Daniel, Legrain, Christianne, Glansdorff, Nicolas
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 2004
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC305743/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14702303/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JB.186.2.351-355.2004
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