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Nucleic acid sensing Toll-like receptors in autoimmunity

Trafficking and activation of the nucleic acid sensing TLRs is subject to unique regulatory requirements imposed by the risk of self-recognition. Like all TLRs these receptors traffick through the Golgi, however, access to the secretory pathway is controlled by a binding partner present in the ER. R...

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Autors principals: Ewald, Sarah E., Barton, Gregory M.
Format: Artigo
Idioma:Inglês
Publicat: 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3057394/
https://ncbi.nlm.nih.gov/pubmed/21146971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coi.2010.11.006
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