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The iron chelator, desferrioxamine, reduces inflammation and atherosclerotic lesion development in experimental mice

OBJECTIVE: Vascular inflammation and monocyte recruitment are initiating events in atherosclerosis that have been suggested to be caused, in part, by iron-mediated oxidative stress and shifts in the intracellular redox environment of vascular cells. Therefore, the objective of this study was to inve...

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Main Authors: Zhang, Wei-Jian, Wei, Hao, Frei, Balz
Formato: Artigo
Idioma:Inglês
Publicado: 2010
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3057189/
https://ncbi.nlm.nih.gov/pubmed/20463304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1258/ebm.2009.009229
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