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The iron chelator, desferrioxamine, reduces inflammation and atherosclerotic lesion development in experimental mice
OBJECTIVE: Vascular inflammation and monocyte recruitment are initiating events in atherosclerosis that have been suggested to be caused, in part, by iron-mediated oxidative stress and shifts in the intracellular redox environment of vascular cells. Therefore, the objective of this study was to inve...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3057189/ https://ncbi.nlm.nih.gov/pubmed/20463304 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1258/ebm.2009.009229 |
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